This second edition of Immunology has been comprehensively updated and features significantly expanded coverage of, for example:
•antigen acquisition and presentation
•regulation of acquired immune responses
•transplantation and tumour immunology
Throughout every chapter the authors have also provided extensive coverage of the applications of immunology to diagnostics in particular.
The inclusion of a glossary in this edition is designed to improve understanding and help students overcome their inherent fear of the complex field of immunology. In addition, this latest edition features two new appendices covering selected cytokines and their functions, and selected CD antigens and their expression, reference material that all those who work in the field will find invaluable.
"…as a work of reference for basic immunological concepts, this book is perfect."
Tove Ragna Reksten, Scandinavian Journal of Immunology
"…The level of information is thorough throughout…[this book] would provide an excellent handbook to junior immunologists (undergraduates, new graduates, research assistants and those new to the subject) by providing a readable and understandable overview, while managing (mostly) not to be too basic or too complex. I would recommend this text book to immunology labs as an early-stage, easily readable guide to the very broad subject area of Immunology…"
Barbara Guinn, Cancer Sciences Division, University of Southampton, UK
1. The immune response explained
2. Components of the immune system
3. Lymphocyte development
4. The innate immune response
5. Antigen acquisition and presentation
6. Generation of adaptive immune responses
7. Regulation of the adaptive immune response
8. Infection and immunity
10. Tolerance and autoimmune disease
11. Transplantation and tumour immunology
13. Immunology in practice
Answers to self-assessment questions
This book aims to cover the basic concepts and practical applications of immunology, introducing this complex field to students in biomedical sciences.
Immunology has 14 chapters, each with self-assessment questions, and three appendices. The book is logically structured, starting with explaining the immune response before taking the reader through the components of the immune system and development of lymphocytes. The basal immunology is finished by covering the innate and adaptive immune response and regulations thereof, and after five chapters on immunology and infection, hypersensitivity, tolerance and autoimmune disease, transplantation and tumour immunology, and immunodeficiencies, practical aspects of immunology and immunotherapy are discussed. The appendices include tables of human CD antigens, selected cytokines and their functions and a thorough glossary.
Each chapter starts with a list of learning objectives with a short summary of what the chapter covers; the figures are simple and easy to understand. In addition, boxes with nice-to-know information are scattered around the book, providing the reader with fun facts and useful definitions that make the complicated subject bearable to read and easier to grasp. The language is simplified compared with other textbooks within this field, which makes this book more reader-friendly, and as the authors have included a list of suggested further reading after each chapter, the reader can easily find the more advanced literature if necessary.
At the first, quick glance, Immunology might appear boring and less attractive to read. The figures are in grey tones, with the exception of an immunohistochemistry figure, as are the few boxes and tables, and the text follows a strict outline. On the other hand, the clean structure to text, figures and boxes renders the book very tidy and easy to read, with no confusing elements. The index guides the reader to the right sections, the glossary provides good definitions and explanations, and the list of human CD antigens is in-depth and up to date. As the book includes no separate chapter on cytokines, the table with selected cytokines and their functions is very useful, also covering the source of the cytokines and the receptors they act upon.
The book does cover the basics of immunology, and serves well as an introductory book to the field. Autoimmune diseases are well described, comprising symptoms and immunological explanations for them where such are known, treatment strategies and future therapies. The chapter on immunology in practice gives a useful overview of the most commonly used techniques. Having a rather small format, it is easy to carry to lectures and the pages have enough space for own notes. As the field of immunology is rapidly evolving and expanding, it is difficult to write books that will always be up-to-date, but as a work of references for basic immunological concepts, this book is perfect.
Scandinavian Journal of Immunology
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